Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Hegemann, Julian David

Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

Lasso peptides are a class of natural products that belong to the family of ribosomally‑assembled and posttranslationally‑modified peptides. They are defined by an unique structural motif referred to as the so‑called lariat knot, whose name is derived from the fact that this topology is reminiscent...

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Bibliographische Detailangaben
1. Verfasser:	Hegemann, Julian David
Beteiligte:	Marahiel, Mohamed A. (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format:	Dissertation
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2014
Schlagworte:	Lassopeptide Epitope Grafting Strukturaufklärung Naturstoffchemie RIPPs epitope grafting Biosynthese lasso peptide ribosomal synthetisierte Naturstoffe ribosomally-assembled natural products Naturstoff Wirkstoffentwicklung Chemie Peptide drug development Biochemie Chemistry & allied sciences
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Genome Mining, Isolation and Characterization of Novel Lasso Peptides and Their Utilization in Drug Development

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