Characterization of the CRISPR-Cas subtype I-B proteins Cas6b and Cas8b of Methanococcus maripaludis C5

The CRISPR-Cas system is an adaptive immune system found in archaea and bacteria to defend themselves against mobile genetic elements (e.g. phages). The system employs base complementarity of small RNA species (crRNAs) to target the foreign nucleic acids for degradation. The hallmark of the syste...

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Bibliographic Details
Main Author: Richter, Hagen Klaus Gunther
Contributors: Randau, Lennart (Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2013
Online Access:PDF Full Text
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