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The analysis of programmed cell death and sporulation in Myxococcus xanthus developmental program
Coordinated behavior and the differentiation of genetic identical cells into distinct cell types have been described for several prokaryotic model species among which is Myxococcus xanthus. Upon nutrient starvation, M. xanthus undergoes a complex developmental life cycle, in which vegetative cells d...
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| Format: | Doctoral Thesis |
| Language: | English |
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Philipps-Universität Marburg
2014
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| Online Access: | PDF Full Text |
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| Summary: | Coordinated behavior and the differentiation of genetic identical cells into distinct cell types have been described for several prokaryotic model species among which is Myxococcus xanthus. Upon nutrient starvation, M. xanthus undergoes a complex developmental life cycle, in which vegetative cells differentiate into environmentally resistant spores. During the developmental program the cells enter one of at least three different cell fate paths, namely “programmed cell death”, sporulation and the differentiation into a persister-like state called “peripheral rods”. The first two cell fates, “cell lysis” and “sporulation”, were examined in the current study. |
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| DOI: | 10.17192/z2014.0063 |