Evaluation des oral verfügbaren Smoothened-Antagonisten LDE225 zur Therapie von Inselzelltumoren in der transgenen Rip1Tag2-Maus

Der Hedgehog-Signalweg und sein Rezeptor Smoothened konnten in vorausgegangenen Studien als potenzieller therapeutischer Angriffspunkt bei pankreatischen neuroendokrinen Neoplasien identifiziert werden. Ziel dieser Arbeit war die Evaluation des oral bioverfügbaren Smo-Antagonisten LDE225 als neue Th...

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Bibliographic Details
Main Author: Wiese, Dominik
Contributors: Fendrich, Volker (Prof. Dr. med.) (Thesis advisor)
Format: Dissertation
Language:German
Published: Philipps-Universität Marburg 2013
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Call Number: urn:nbn:de:hebis:04-z2013-06777
Downloads: 9 (2022), 153 (2021), 190 (2020), 206 (2019), 66 (2018)
Publication Date: 2013-11-25
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author. https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2013/0677
https://doi.org/10.17192/z2013.0677