Interaction dynamics between heterotrimeric G-proteins and type V adenylyl cyclase determine sensitivity of effector regulation

The signalling pathway from G-protein-coupled receptors to the second messenger cAMP is present in virtually all cells and of major physiological and pathophysiological importance. The membrane-spanning receptors can easily be targeted by pharmaceutical compounds and therapies to treat diseases like...

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Bibliographic Details

Main Author:	Milde, Markus
Contributors:	Bünemann, Moritz (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2013
Subjects:	Adenylylzyklase Dynamik G-protein cAMP FRET Fluoreszenz-Resonanz-Energie-Transfer adenylyl cyclase Medizin Interaktion interaction G-Protein Medical sciences Medicine
Online Access:	PDF Full Text
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