Investigations into the mechanism of the coenzyme B12 dependent reaction catalyzed by glutamate mutase from Clostridium cochlearium

Aims of this study were the search for inhibitors of the coenzyme B12-dependent glutamate mutase and for insight into the first step of its catalytic mechanism, the homolytic cleavage of the cobalt-carbon bond. Glutamate mutase is composed of two separately isolated protein components S and E2, whic...

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Bibliographic Details
Main Author: Lyatuu, Fredrick Edwin
Contributors: Buckel, W. (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2012
Online Access:PDF Full Text
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