Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding

Pituitary adenylate cyclase-activating polypeptide mediates differential signaling through PAC1 receptor splice variants and activates non-canonical cAMP dependent gene induction in the nervous system - Implications for homeostatic stress-responding

Pituitary adenylate cyclase-activating polypeptide (PACAP)-mediated activation of its G protein-coupled receptor PAC1 results in activation of the two G proteins Gs and Gq to alter second messenger generation and gene transcription in the nervous system, important for homeostatic responses to stress...

Full description

Saved in:
Bibliographic Details
Main Author: Holighaus, Yvonne
Contributors: Weihe, Eberhard (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2011
Subjects:
PACAP
nervous system
G protein-coupled receptors
neuropharmacology
Stress
signal transduction
Genexpression
Naturwissenschaften
Signaltransduktion
Neuropharmakologie
neuropeptides
G-Protein gekoppelte Rezeptoren
gene expression
Neuropeptide
stress
Nervensystem
Natural sciences & mathematics
Online Access:PDF Full Text
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

PDF Full Text

Holdings details from
Call Number: urn:nbn:de:hebis:04-z2011-05513
Publication Date: 2011-08-29
Date of Acceptance: 2011-08-01
Downloads: 17 (2023), 75 (2022), 124 (2021), 112 (2020), 151 (2019), 26 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2011/0551
https://doi.org/10.17192/z2011.0551
Copy

Similar Items