Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.

Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...

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Bibliographic Details
Main Author: Kumari, Ashu
Contributors: Burchert, Andreas (Prof Dr. ) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2011
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Call Number: urn:nbn:de:hebis:04-z2011-04590
Publication Date: 2011-08-10
Date of Acceptance: 2011-07-26
Downloads: 49 (2024), 68 (2023), 63 (2022), 45 (2021), 80 (2020), 34 (2019), 25 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2011/0459
https://doi.org/10.17192/z2011.0459