Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.

Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...

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Bibliographic Details

Main Author:	Kumari, Ashu
Contributors:	Burchert, Andreas (Prof Dr. ) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2011
Subjects:	chronic mayeloid leukemia Imatinib mesilat Chronisch-myeloische Leukämie Resistenz resistance Medizin Imatinib mesylate Medical sciences Medicine
Online Access:	PDF Full Text
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