Elucidation of mechanism of disease resistance and persistence in chronic myeloid leukemia.

Chronic myeloid leukemia (CML) is a clonal disorder of the hematopoietic stem cell caused by the BCR-ABL receptor tyrosine kinase. Imatinib mesylate (IM) is an inhibitor of BCR-ABL and has been approved for the treatment of CML. IM is well tolerated and highly efficacious as it induces stable long-t...

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Bibliographic Details
Main Author: Kumari, Ashu
Contributors: Burchert, Andreas (Prof Dr. ) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2011
Online Access:PDF Full Text
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