Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...

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Bibliographic Details

Main Author:	Wohlfahrt, Martin E.
Contributors:	Lingelbach, Klaus (Prof.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2010
Subjects:	Onkolyse Glioblastom Adenovirus 5 Glioblastoma multiforme, TRAIL TRAIL Oncolysis Naturwissenschaften Adenovirus Natural sciences & mathematics
Online Access:	PDF Full Text
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