Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.

Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...

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Bibliographic Details
Main Author: Wohlfahrt, Martin E.
Contributors: Lingelbach, Klaus (Prof.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2010
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Call Number: urn:nbn:de:hebis:04-z2010-06444
Downloads: 76 (2021), 72 (2020), 93 (2019), 48 (2018), 63 (2017)
Source: A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Res. 2007 Sep 15;67(18):8783-90. PMID: 17875719
Publication Date: 2010-12-02
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author.
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