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Analysis of a capsid-modified and conditionally replicating, oncolytic adenoviral vector as a novel treatment for human glioblastoma multiforme.
Glioblastoma multiforme (GBM) is the most aggressive brain tumor, and patients rarely survive for more than 2 years. Gene therapy may offer new treatment options and improve the prognosis for patients with GBM. Adenovirus-mediated gene therapy strategies for brain tumors have been limited by ineffic...
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| Beteiligte: | |
| Format: | Dissertation |
| Sprache: | Englisch |
| Veröffentlicht: |
Philipps-Universität Marburg
2010
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| Schlagworte: | |
| Online Zugang: | PDF-Volltext |
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PDF-Volltext| Signatur: |
urn:nbn:de:hebis:04-z2010-06444 |
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| Publikationsdatum: |
2010-12-02 |
| Quelle: |
A capsid-modified, conditionally replicating oncolytic adenovirus vector expressing TRAIL Leads to enhanced cancer cell killing in human glioblastoma models. Cancer Res. 2007 Sep 15;67(18):8783-90. PMID: 17875719 |
| Datum der Annahme: |
2010-07-08 |
| Downloads: |
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| Lizenz: |
https://rightsstatements.org/vocab/InC-NC/1.0/ |
| Zugangs-URL: |
https://archiv.ub.uni-marburg.de/diss/z2010/0644 https://doi.org/10.17192/z2010.0644 |