Chemoenzymatic Synthesis of Chromodepsipeptides and Natural Product Discovery via Genome Mining

Recent advances in the development of sequencing technologies have enabled the identification of a multitude of bacterial gene clusters, putatively involved in the biosynthesis of nonribosomal peptides (NRPs). Peptides of nonribosomal origin constitute a class of structurally and functionally divers...

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Bibliographic Details

Main Author:	Robbel, Lars
Contributors:	Marahiel, Mohamed (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	German
Published:	Philipps-Universität Marburg 2010
Subjects:	Thioesterase II Chemie Modifikation <Biochemie> NRPS Sekundärmetabolit Genanalyse Genomische Mining acetylation Hydroxylierung genome mining Acetylierung hydroxylation cyclodimerization Zyklodimerisierung Chemistry & allied sciences
Online Access:	PDF Full Text
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