Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

In this thesis, toxicity of PEI-based non-viral vector systems for siRNA application into the lungs was comprehensively described and analyzed in vitro as well as in vivo. Chapter 1 introduced in basic information about the lung anatomy and physiology and general considerations for pulmonary appli...

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Bibliographic Details
Main Author: Beyerle, Andrea
Contributors: Kissel, Thomas (Prof.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2010
Subjects:
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