Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

Toxicological Evaluation of Poly(ethylene imine) -based non-viral vector systems for pulmonary siRNA application

In this thesis, toxicity of PEI-based non-viral vector systems for siRNA application into the lungs was comprehensively described and analyzed in vitro as well as in vivo. Chapter 1 introduced in basic information about the lung anatomy and physiology and general considerations for pulmonary appli...

Full description

Saved in:
Bibliographic Details
Main Author: Beyerle, Andrea
Contributors: Kissel, Thomas (Prof.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2010
Subjects:
RNS-Interferenz
Toxikologische Bewertung
Naturwissenschaften
inflammation
Wasserlösliche Polymere
Oxidativer Stress
Poly(ethylene imine)
oxidative stress
pulmonary application
Entzündung
In vivo
Lunge
Cytotoxizität
In vitro
siRNA
Polyethylenimin (PEI)
Cytotoxicity
Natural sciences & mathematics
Online Access:PDF Full Text
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

PDF Full Text

Holdings details from
Call Number: urn:nbn:de:hebis:04-z2010-01360
Publication Date: 2010-05-10
Date of Acceptance: 2010-04-14
Downloads: 82 (2024), 81 (2023), 178 (2022), 275 (2021), 207 (2020), 440 (2019), 250 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2010/0136
https://doi.org/10.17192/z2010.0136

Similar Items