Regulation of proto-oncogenic Pim-1 kinase and miR-17-92 microRNAcluster in the human leukemia cell line K562

In this thesis the regulation of the oncogenic kinase Pim-1 and the microRNA cluster miR-17-92 has been investigated using the leukemia cell line K562 as a model system. Pim-1 and miR-17-92 have been reported to be highly expressed in the context of leukemia cells as well as in other cancer cell lin...

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Bibliographic Details

Main Author:	Prinz, Robert
Contributors:	Hartmann, Roland Karl (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2009
Subjects:	K562 Leukämie Naturwissenschaften miR-17-92 Pim-1 Cancer miR-33 Krebs Small RNA Antisense-RNS B-Zell-Leukämie Gen-Targeting Natural sciences & mathematics
Online Access:	PDF Full Text
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