Regulation of proto-oncogenic Pim-1 kinase and miR-17-92 microRNAcluster in the human leukemia cell line K562

In this thesis the regulation of the oncogenic kinase Pim-1 and the microRNA cluster miR-17-92 has been investigated using the leukemia cell line K562 as a model system. Pim-1 and miR-17-92 have been reported to be highly expressed in the context of leukemia cells as well as in other cancer cell lin...

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Bibliographic Details
Main Author: Prinz, Robert
Contributors: Hartmann, Roland Karl (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Published: Philipps-Universität Marburg 2009
Online Access:PDF Full Text
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