Investigation of the functions of 53BP1 in DNA demethylation

DNA damage can be caused by various forms of genotoxic stress, including endogenous (reactive oxygen species, abnormal replication intermediates) and exogenous (UV, IR, and reactive chemicals) sources. DNA double-strand break (DSB) is believed to be one of the most serious lesions to cells becaus...

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Bibliographic Details

Main Author:	Wang, Linfang
Contributors:	Engenhart-Cabillic, R. (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2009
Subjects:	Medizin DNA-Demethylierung DNA demethylation Demethylierung Medical sciences Medicine
Online Access:	PDF Full Text
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