Unusual Building Blocks and Domain Organization of Non-Ribosomal Peptide Synthetases

The diverse class of non-ribosomal peptides consists of manifold pharmacologically important natural products. They are clinically used in antibiotic, antiviral and antitumor therapy, furthermore some are known immunosuppresants. The biological activity is based on their structural diversity, as the...

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Bibliographic Details

Main Author:	Strieker, Matthias
Contributors:	Marahiel, Mohamed A. (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2009
Subjects:	Naturstoff Hydroxylierung Beta-hydroxyaminosäuren Tailoring NRPS Modifikation <Biochemie> Antibiotics Nonproteinogenic amino acids Chemie Antibiotikum Modification Aminosäuren Chemistry & allied sciences
Online Access:	PDF Full Text
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