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Non-Viral Delivery of Nucleic Acids and Image-Guided Assessment of in vivo Performance of Multifunctional Nanomedicines

In this thesis, new and multifunctional non-viral vectors for delivery of nucleic acids were synthesized and characterized concerning biophysicochemical parameters. Chapter 1 introduces into the field of nanomedicine which advanced drug delivery systems can be numbered among. Chapter 2 describes t...

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Bibliographic Details
Main Author: Merkel, Olivia Monika
Contributors: Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2009
Subjects:
Radionuklid
Gene Knockdown Techniques
Polyethylenimin
Tierm
Small Interfering RNA
Pharmacokinetics
Polyethyleneimine
Pharmakokinetik
Polymere
Gamma Camera Imaging
Biodistribution
Nanotechnologie
RNS-Interferenz
Gentherapie
Naturwissenschaften
Gene Delivery
SPECT
Polyethyleniminderivate
Natural sciences & mathematics
Online Access:PDF Full Text
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