Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Parthasarathy, Anutthaman

Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

Muconyl-CoA, 2-hydroxyadipoyl-CoA, oxalocrotonyl-CoA and butynedioyl- CoA were synthesised and characterised as substrates of the (R)-2- hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum. The specificity of the enzyme for these substrates were determined and the reaction products identi...

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Bibliographische Detailangaben
1. Verfasser:	Parthasarathy, Anutthaman
Beteiligte:	Buckel, Wolfgang (Prof. Dr.) (BetreuerIn (Doktorarbeit))
Format:	Dissertation
Sprache:	Englisch
Veröffentlicht:	Philipps-Universität Marburg 2009
Schlagworte:	[4Fe-4S] Cluster Hydroxyglutaryl-CoA-Dehydratase <2-> Clostridium propionicum 2-hydroxyglutaryl-CoA, lactyl-CoA 2-Hydroxyglutarat-Dehydrogenase Biowissenschaften, Biologie Coenzym A Clostridium symbiosum Acidaminococcus fermentans Dehydratase Lactyl-CoA, Dehydration [4Fe-4S] cluster Life sciences
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Substrates and mechanism of 2-hydroxyglutaryl-CoA-dehydratase from Clostridium symbiosum

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