Non-Viral Gene Delivery Systems: Studies on HER2-Targeted PEG-PEI Copolymers and Modified Chitosans

In this thesis new non-viral gene delivery systems were synthesized and characterized. In the first part different questions concerning in vitro and in vivo gene delivery using HER2-targeted Polyethylenglycol (PEG)-modified Polyethylenimine (PEI) polyplexes were addressed. The second part deals with...

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Bibliographic Details

Main Author:	Germershaus, Oliver
Contributors:	Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2008
Subjects:	Gentransfer Biodistribution Pharmacokinetics Polyethylenimine Modified Polymers Polyethylenimin Gene therapy Modifizierte Polymere Naturwissenschaften Tiermodell Polyethyleniminderivate Pharmakokinetik Plasmid Zellkultur Natural sciences & mathematics
Online Access:	PDF Full Text
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