Structure-based Inhibitor Design for the Antimalarial Target Plasmepsin

The protozoan disease malaria is one of the major inexorable infections worldwide, especially widespread throughout tropical regions. It is caused by parasites of the genus Plasmodium (P. falciparum, P. vivax, P. malariae and P. ovale) and transmitted by female Anopheles mosquitoes. The WHO estimate...

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Bibliographic Details

Main Author:	Luksch, Torsten
Contributors:	Klebe, Gerhard (Prof.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2008
Subjects:	Wirkstoffdesign Molecular Dynamics Plasmepsin Malaria Docking Medizin MD Simulation Drug Design Medical sciences Medicine
Online Access:	PDF Full Text
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