Molekulare Charkterisierung von Methicillin-resistenen Staphylococcus aureus mittels spa-Typisierung

Molekulare Charkterisierung von Methicillin-resistenen Staphylococcus aureus mittels spa-Typisierung

Methicillin-resistente Staphylococcus aureus gehören zu den Haupterregern nosokomialer Infektionen, die von leichten Weichteil- und Hautinfektionen bis hin zur Pneumonie oder Sepsis auch zu lebensbedrohlichen Erkrankungen wie das Toxic Shock Syndrom (TSS) reichen. Die Entwicklung von Antibiotikares...

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Bibliographic Details
Main Author: Wewers, Kristina
Contributors: Mutters, Reiner (Prof, Dr) (Thesis advisor)
Format: Doctoral Thesis
Language:German
Published: Philipps-Universität Marburg 2008
Subjects:
Pulsfeld-Gelelektrophorese
MRSA
Medizin
DNS-Sequenz
Spa typing
Spa Typisierung
Protein A
Medical sciences Medicine
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Methicillin-resistent staphylococcus aureus strains were investigate by two molecular typing methods, typing of protein A (spa) and pulsed-field gel electrophoresis (PFGE). Pulsed-field electrophoresis is known as goldstandard in typing MRSA strain. In the results typing of protein A (spa), which is supported by a new software (RidimStaph(R)), has got the same discriminatory power as pulsed-field gel electrophoresis. The advantage of spa-typing is less time for identification of MRSA-strains and the easier handling.

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