Macrocyclization and Fatty Acid Modification during the Synthesis of Nonribosomal Peptides

Nonribosomal peptides (NRPs) constitute a large and diverse class of pharmacologically important natural products that find useful therapeutic application as immunosuppressants, antibiotics, or anticancer agents. The biological activity of many of these compounds relies on the macrocyclic structure...

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Bibliographic Details

Main Author:	Kopp, Florian
Contributors:	Marahiel, M. A. (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2008
Subjects:	Peptidsynthetasen Lipopeptide Antbiotics Fatty Acid Modification Peptidantibiotikum Fettsäuremodifikation Peptidemacrocyclization Chemie Peptidsynthese Nonribosomal Peptide Synthetases Lipopeptidantibiotika Pepdtidmakrozyklisierung Chemistry & allied sciences
Online Access:	PDF Full Text
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