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Modified Poly(ethylene imines) for plasmid delivery: Physico-chemical and in vitro/in vivo investigations

This thesis describes the development of poly(ethylene imine) (PEI) conjugates as vector systems for plasmid delivery. Conjugates were synthesized and characterized regarding their suitability as non-viral vector systems for in vivo administration. Chapter 1 gives a detailed overview of the curren...

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Bibliographic Details
Main Author: Neu, Michael
Contributors: Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format: Doctoral Thesis
Language:English
Published: Philipps-Universität Marburg 2006
Subjects:
Pharmakokinetik
Polyethylenglykole
Quervernetzung
Plasmid
Poly(ethylene glycol)
Crosslinking
Poly(etyhlene imine)
Naturwissenschaften
Gene therapy
Gentherapie
Polyethylenimin
Pharmacokinetics
Natural sciences & mathematics
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Call Number: urn:nbn:de:hebis:04-z2007-00896
Publication Date: 2007-03-01
Date of Acceptance: 2006-11-22
Source: Journal of Gene Medicine 7 (2005), 992-1009; Journal of Controlled Release 109, 1-3 (2005), 299–316; Biomacromolecules. 2006 Dec, 7(12):3428-38, Journal of Controlled Release (2007)
Downloads: 79 (2024), 52 (2023), 195 (2022), 282 (2021), 270 (2020), 346 (2019), 154 (2018)
License: https://rightsstatements.org/vocab/InC-NC/1.0/
Access URL: https://archiv.ub.uni-marburg.de/diss/z2007/0089
https://doi.org/10.17192/z2007.0089

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