Modified Poly(ethylene imines) for plasmid delivery: Physico-chemical and in vitro/in vivo investigations

This thesis describes the development of poly(ethylene imine) (PEI) conjugates as vector systems for plasmid delivery. Conjugates were synthesized and characterized regarding their suitability as non-viral vector systems for in vivo administration. Chapter 1 gives a detailed overview of the curren...

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Bibliographic Details

Main Author:	Neu, Michael
Contributors:	Kissel, Thomas (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2006
Subjects:	Pharmakokinetik Polyethylenglykole Quervernetzung Plasmid Poly(ethylene glycol) Crosslinking Poly(etyhlene imine) Naturwissenschaften Gene therapy Gentherapie Polyethylenimin Pharmacokinetics Natural sciences & mathematics
Online Access:	PDF Full Text
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