The surfactin biosynthetic complex of Bacillus subtilis: COM domain-mediated biocombinatorial synthesis, and single step purification of native multi-modular NRPSs and multi-enzyme complexes

Most biosynthetic templates for the assembly of peptide natural products are composed of two or more nonribosomal peptide synthetases (NRPSs). For example, the surfactin biosynthetic complex consists of three NRPSs (SrfA-A, SrfA-B, and SrfA-C), which are encoded by the polycistronic srfA operon with...

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Bibliographic Details
Main Author: Chiocchini, Claudia
Contributors: Buckel, Wolfgang (Prof.) (Thesis advisor)
Format: Dissertation
Published: Philipps-Universität Marburg 2006
Online Access:PDF Full Text
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Call Number: urn:nbn:de:hebis:04-z2006-08381
Downloads: 81 (2021), 65 (2020), 71 (2019), 38 (2018), 64 (2017)
Publication Date: 2006-12-21
License: According to UrhG § 31 (2), the author has granted the University Library Marburg the right of use for electronic publication on the Internet and for archiving on its archive server. He has declared that with the granting of the right of use according to UrhG § 31 (3) no exclusive rights of third parties are violated. All other rights for the exploitation of the publication remain with the author.
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