Characterization of a major neutralizing epitope on the yellow fever virus envelope protein using human recombinant monoclonal antibody fragments generated by phage display

Yellow fever virus (YFV) is a mosquito-transmitted, enveloped, positive stranded RNA virus belonging to the genus flavivirus, which causes hemorrhagic fever in humans in Africa and South America. The YFV is responsible for 200 000 clinical infections per year including 40 000 deaths. Despite the pre...

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Bibliographic Details

Main Author:	Daffis, Stephane
Contributors:	ter Meulen, Jan (Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2006
Subjects:	Gelbfieber Yellow fever virus Phage display Neutralizing epitopes Flaviviren Gelbfiebervirus Phagen-Display-Bibliothek Antibody fragments Impfstoff Virologie Medizin Medical sciences Medicine
Online Access:	PDF Full Text
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