Zebrafish Trap230/Med12 is required for Sox9 activity and limb induction

This thesis deals with the mapping and cloning of trapped (tpd), a novel zebrafish mutant found to disrupt an ortholog of Trap230, a member of the Mediator complex. Mediator is a coactivator complex transducing the interaction of DNA-binding transcription factors with RNA polymerase II. The vert...

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Bibliographic Details
Main Author: Rau, Marlene Juliane
Contributors: Renkawitz-Pohl, Renate (Prof. Dr.) (Thesis advisor)
Format: Dissertation
Language:English
Published: Philipps-Universität Marburg 2005
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Online Access:PDF Full Text
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