Novel Strategies for Model-Building of G Protein-Coupled Receptors

The G protein-coupled receptors constitute still the most densely populated proteinfamily encompassing numerous disease-relevant drug targets. Consequently, medicinal chemistry is expected to pursue targets from that protein family in that hits need to be generated and subsequently optimized towards...

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Bibliographic Details

Main Author:	van Neuren, Anske Stephanie
Contributors:	Klebe, Gerhard (Prof. Dr.) (Thesis advisor)
Format:	Doctoral Thesis
Language:	English
Published:	Philipps-Universität Marburg 2003
Subjects:	GTP-bindende Proteine GPCR G-Proteine Molekulardesign Medizin G protein coupled receptors Computational chemistry Arzneimitteldesign Membranproteine G protein-gekuppelte Rezeptoren Molecular design Ligand docking Drug design Medical sciences Medicine
Online Access:	PDF Full Text
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