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The Role of TGF-β1 and Mutant SMAD4 on Epithelial-Mesenchymal Transition Features in Head and Neck Squamous Cell Carcinoma Cell Lines

Head and neck squamous cell carcinomas (HNSCCs) represent more than 90% of all malignancies in the upper aero-digestive tract. Their ability to metastasize is tightly associated with the patient’s survival. The process of epithelial–mesenchymal transition (EMT) is thought to be a central mechanism f...

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Main Authors: Bette, Michael, Reinhardt, Laura, Gansukh, Uyanga, Xiang-Tischhauser, Li, Meskeh, Haifa, Di Fazio, Pietro, Buchholz, Malte, Stuck, Boris A., Mandic, Robert
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
epithelial–mesenchymal transition
SMAD4
Medizin
TGF-β1
head and neck squamous cell carcinoma
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2025-00124
Publication Date: 2025-01-14
Source: Erstveröffentlichung: Bette, M.; Reinhardt, L.; Gansukh, U.; Xiang-Tischhauser, L.; Meskeh, H.; Di Fazio, P.; Buchholz, M.; Stuck, B.A.; Mandic, R. The Role of TGF-β1 and Mutant SMAD4 on Epithelial-Mesenchymal Transition Features in Head and Neck Squamous Cell Carcinoma Cell Lines. Cancers 2024, 16, 3172. https://doi.org/10.3390/cancers16183172
Downloads: 6 (2025)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2025/0012
https://doi.org/10.3390/cancers16183172

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