Current Knowledge about Nonclassical Monocytes in Patients with Multiple Sclerosis, a Systematic Review
Monocytes play a critical role in the initiation and progression of multiple sclerosis (MS). Recent research indicates the importance of considering the roles of monocytes in the management of MS and the development of effective interventions. This systematic review examined published research on...
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| Main Author: | |
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| Format: | Article |
| Language: | English |
| Published: |
Philipps-Universität Marburg
2024
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| Subjects: | |
| Online Access: | PDF Full Text |
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| Summary: | Monocytes play a critical role in the initiation and progression of multiple sclerosis (MS).
Recent research indicates the importance of considering the roles of monocytes in the management
of MS and the development of effective interventions. This systematic review examined published
research on the roles of nonclassical monocytes in MS and how they influence disease management.
Reputable databases, such as PubMed, EMBASE, Cochrane, and Google Scholar, were searched for
relevant studies on the influence of monocytes on MS. The search focused on studies on humans and
patients with experimental autoimmune encephalomyelitis (EAE) published between 2014 and 2024
to provide insights into the study topic. Fourteen articles that examined the role of monocytes in MS
were identified; the findings reported in these articles revealed that nonclassical monocytes could
act as MS biomarkers, aid in the development of therapeutic interventions, reveal disease pathology,
and improve approaches for monitoring disease progression. This review provides support for the
consideration of monocytes when researching effective diagnostics, therapeutic interventions, and
procedures for managing MS pathophysiology. These findings may guide future research aimed at
gaining further insights into the role of monocytes in MS. |
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| Item Description: | Gefördert durch den Open-Access-Publikationsfonds der UB Marburg. |
| DOI: | 10.3390/ijms25137372 |