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Improving the pharmacokinetics, biodistribution and plasma stability of monobodies

Cancer is a leading cause of death worldwide. Several targeted anticancer drugs entered clinical practice and improved survival of cancer patients with selected tumor types, but therapy resistance and metastatic disease remains a challenge. A major class of targeted anticancer drugs are therapeut...

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Bibliographic Details
Main Authors: Dinh-Fricke, Adrian Valentin, Hantschel, Oliver
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
protein therapeutics
albumin binding domain
pharmacokinetics
Medizin
monobody
protein engineering
targeted therapies
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2024-09070
Publication Date: 2024-05-16
Source: Erstveröffentlichung: Dinh-Fricke AV and Hantschel O (2024), Improving the pharmacokinetics, biodistribution and plasma stability of monobodies. Front. Pharmacol. 15:1393112. https://doi.org/ 10.3389/fphar.2024.1393112
Downloads: 23 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0907
https://doi.org/10.3389/fphar.2024.1393112

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