Improving the pharmacokinetics, biodistribution and plasma stability of monobodies

Cancer is a leading cause of death worldwide. Several targeted anticancer drugs entered clinical practice and improved survival of cancer patients with selected tumor types, but therapy resistance and metastatic disease remains a challenge. A major class of targeted anticancer drugs are therapeut...

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Bibliographic Details

Main Authors:	Dinh-Fricke, Adrian Valentin, Hantschel, Oliver
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2024
Subjects:	protein therapeutics albumin binding domain pharmacokinetics Medizin monobody protein engineering targeted therapies Medical sciences Medicine
Online Access:	PDF Full Text
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