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Hype or hope? High placebo response in major depression treatment with ketamine and esketamine: a systematic review and meta-analysis

Background: Ketamine and esketamine offer a novel approach in the pharmacological treatment of major depressive disorder (MDD). This metaanalysis aimed to investigate the placebo response in double-blind, randomized controlled studies (RCTs) on patients with MDD receiving ketamine or esketamine....

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Main Authors: Matsingos, Alexandros, Wilhelm, Marcel, Noor, Laila, Yildiz, Cüneyt, Rief, Winfried, Hofman, Stefan G., Falkenberg, Irina, Kircher, Thilo
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
Medizin
treatment expectation
placebo
NMDA-receptor antagonist
esketamine
psychoactive medication
depression (MDD)
ketamine
placebo response
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2024-08866
Publication Date: 2024-04-23
Source: Erstveröffentlichung: Matsingos A, Wilhelm M, Noor L, Yildiz C, Rief W, Hofmann SG, Falkenberg I and Kircher T (2024) Hype or hope? High placebo response in major depression treatment with ketamine and esketamine: a systematic review and meta-analysis. Front. Psychiatry 15:1346697. https://doi.org/10.3389/fpsyt.2024.1346697
Downloads: 21 (2025), 38 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0886
https://doi.org/10.3389/fpsyt.2024.1346697

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