Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes

Two recent studies published in Nature focused on the clinical efficacy of the menin inhibitor revumenib (SNDX-5613) in KMT2A (histone-lysine N-methyltransferase 2A)-rearranged or NPM1 (Nucleophosmin1)-mutant acute myeloid leukemia.1,2 These studies indicate that menin inhibition and its acquired re...

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Main Author: Di Fazio, Pietro
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
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Call Number: urn:nbn:de:hebis:04-es2024-08821
Publication Date: 2024-04-23
Source: Erstveröffentlichung: Di Fazio, P. Targeting menin: a promising therapeutic strategy for susceptible acute leukemia subtypes. Sig Transduct Target Ther 8, 384 (2023). https://doi.org/10.1038/s41392-023-01627-w
Downloads: 31 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0882
https://doi.org/10.1038/s41392-023-01627-w