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Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential

Mitochondrial dysfunction is strongly implicated in the etiology of idiopathic and genetic Parkinson’s disease (PD). However, strategies aimed at ameliorating mitochondrial dysfunction, including antioxidants, antidiabetic drugs, and iron chelators, have failed in disease-modification clinical tri...

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Bibliographic Details
Main Authors: Henrich, Martin T., Oertel, Wolfgang H., Surmeier, D. James, Geibl, Fanni F.
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
Mitochondria
Mitochondrial dysfunction
Synuclein
Parkinson’s disease
Medizin
MPTP
Neuroprotective therapies
Electron transport chain, Antioxidants
Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2024-08745
Publication Date: 2024-04-18
Source: Erstveröffentlichung: Henrich, M.T., Oertel, W.H., Surmeier, D.J. et al. Mitochondrial dysfunction in Parkinson’s disease – a key disease hallmark with therapeutic potential. Mol Neurodegeneration 18, 83 (2023). https://doi.org/10.1186/s13024-023-00676-7
Downloads: 4 (2025), 110 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0874
https://doi.org/10.1186/s13024-023-00676-7

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