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Identification of NAD-RNA species and ADPR-RNA decapping in Archaea

NAD is a coenzyme central tometabolism that also serves as a 5′-terminal cap for bacterial and eukaryotic transcripts. Thermal degradation of NAD can generate nicotinamide and ADP-ribose (ADPR). Here, we use LC-MS/MS and NAD captureSeq to detect and identify NAD-RNAs in the thermophilic model ar...

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Main Authors: Gomes-Filho, José Vicente, Breuer, Ruth, Morales-Filloy, Hector Gabriel, Pozhydaieva, Nadiia, Borst, Andreas, Paczia, Nicole, Soppa, Jörg, Höfer, Katharina, Jäschke, Andres, Randau, Lennart
Format: Article
Language:English
Published: Philipps-Universität Marburg 2024
Subjects:
Biowissenschaften, Biologie
Archaeal physiology
RNA modification
Archaeal biology
Life sciences
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Call Number: urn:nbn:de:hebis:04-es2024-08736
Publication Date: 2024-04-18
Source: Erstveröffentlichung: Gomes-Filho, J.V., Breuer, R., Morales-Filloy, H.G. et al. Identification of NAD-RNA species and ADPR-RNA decapping in Archaea. Nat Commun 14, 7597 (2023). https://doi.org/10.1038/s41467-023-43377-x
Downloads: 14 (2025), 66 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0873
https://doi.org/10.1038/s41467-023-43377-x

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