Identification of NAD-RNA species and ADPR-RNA decapping in Archaea

NAD is a coenzyme central tometabolism that also serves as a 5′-terminal cap for bacterial and eukaryotic transcripts. Thermal degradation of NAD can generate nicotinamide and ADP-ribose (ADPR). Here, we use LC-MS/MS and NAD captureSeq to detect and identify NAD-RNAs in the thermophilic model ar...

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Main Authors: Gomes-Filho, José Vicente, Breuer, Ruth, Morales-Filloy, Hector Gabriel, Pozhydaieva, Nadiia, Borst, Andreas, Paczia, Nicole, Soppa, Jörg, Höfer, Katharina, Jäschke, Andres, Randau, Lennart
Format: Article
Published: Philipps-Universität Marburg 2024
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