Molecular modeling and phylogenetic analyses highlight the role of amino acid 347 of the N1 subtype neuraminidase in influenza virus host range and interspecies adaptation
The N1 neuraminidases (NAs) of avian and pandemic human influenza viruses contain tyrosine and asparagine, respectively, at position 347 on the rim of the catalytic site; the biological significance of this difference is not clear. Here, we used molecular dynamics simulation to model the effects...
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Language: | English |
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Philipps-Universität Marburg
2023
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urn:nbn:de:hebis:04-es2024-08091 |
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2024-01-24 |
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Erstveröffentlichung: Elli S, Raffaini G, Guerrini M, Kosakovsky Pond S and Matrosovich M (2023) Molecular modeling and phylogenetic analyses highlight the role of amino acid 347 of the N1 subtype neuraminidase in influenza virus host range and interspecies adaptation. Front. Microbiol. 14:1309156. https://doi.org/10.3389/fmicb.2023.1309156 |
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41 (2024) |
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https://archiv.ub.uni-marburg.de/es/2024/0809 https://doi.org/10.3389/fmicb.2023.1309156 |