Crystallographic Fragment Screening on the Shigella Type III Secretion System Chaperone IpgC

The Shigella pathogenicity factor IpgC belongs to the class II of type III secretion system chaperones, whose members are characterized by a tetratricopeptide repeat (TPR) domain consisting of three and a half TPR motifs. Since IpgC is essential for Shigella virulence, we determined a high-resolu...

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Main Authors: Gárdonyi, Marina, Hasewinkel, Christian, Wallbaum, Johanna, Wollenhapt, Jan, Weiss, Manfred S., Klebe, Gerhard, Reuter, Klaus, Heine, Andreas
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
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Call Number: urn:nbn:de:hebis:04-es2024-08037
Publication Date: 2024-01-24
Source: Erstveröffentlichung: Marina Gárdonyi, Christian Hasewinkel, Johanna Wallbaum, Jan Wollenhaupt, Manfred S. Weiss, Gerhard Klebe, Klaus Reuter, and Andreas Heine ACS Omega 2023 8 (48), 46051-46065. https://doi.org/10.1021/acsomega.3c07058
Downloads: 46 (2024)
License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0803
https://doi.org/10.1021/acsomega.3c07058