MAGED2 Depletion Promotes Stress-Induced Autophagy by Impairing the cAMP/PKA Pathway

Melanoma-associated antigen D2 (MAGED2) plays an essential role in activating the cAMP/PKA pathway under hypoxic conditions, which is crucial for stimulating renal salt reabsorption and thus explaining the transient variant of Bartter’s syndrome. The cAMP/PKA pathway is also known to regulate aut...

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Bibliographic Details

Main Authors:	Nasrah, Sadiq, Radi, Aline, Daberkow, Johanna K., Hummler, Helmut, Weber, Stefanie, Seaayfan, Elie, Kömhoff, Martin
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	hypoxia nephrogenesis Bartter’s syndrome cAMP cellular stress autophagy MAGED2 G-alpha-S Medizin Medical sciences Medicine
Online Access:	PDF Full Text
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