First genome-wide association study for lymphatic filariasis in a West African population points to a human leukocyte antigen-me diate d disease pathophysiology

First genome-wide association study for lymphatic filariasis in a West African population points to a human leukocyte antigen-me diate d disease pathophysiology

Lymphatic filariasis (LF) represents a parasitic disease caused by filarial nematodes. Although some infected individuals present an asymptomatic course, others suffer severe chronic lymphatic pathology, including lymphedema, hydrocele, and elephantiasis. Several studies have shown that host genetic...

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Main Authors: Grover, Sandeep, Opoku, Vera S., Debrah, Linda B., Maj, Carlo, Osei-Mensah, Jubin, Mensah, Derrick A., Hoerauf, Achim, Debrah, Alexander Y., Schumacher, Johannes, Pfarr, Kenneth
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
Lymphatic filariasis, Wuchereria bancrofti, Genome-wide association study (GWAS), West African population, Lymphedema, Hydrocele
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Medical sciences Medicine
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Call Number: urn:nbn:de:hebis:04-es2024-04557
Publication Date: 2024-01-18
Source: Erstveröffentlichung: Grover S, Opoku VS, Debrah LB, Maj C, Osei-Mensah J, Mensah DA, Hoerauf A, Debrah AY, Schumacher J, Pfarr K. First genome-wide association study for lymphatic filariasis in a West African population points to a human leukocyte antigen-mediated disease pathophysiology. Int J Infect Dis. 2023 Aug;133:1-4. https://doi.org/10.1016/j.ijid.2023.04.408
Downloads: 26 (2024)
License: https://creativecommons.org/licenses/by-nc-nd/4.0/
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0455
https://doi.org/10.1016/j.ijid.2023.04.408

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