Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats

CACNA1C encodes the pore-forming α1C subunit of the L-type Ca2+ channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c+/− rats represent a recently developed model with a behavioral phenotype, but its cardiac pheno...

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Bibliographic Details

Main Authors:	Fender, Hauke, Walter, Kim, Kiper, Aytug K., Plačkić, Jelena, Kisko, Theresa M., Braun, Moria D., Scharting, Rainer K. W., Rohrbach, Susanne, Wöhr, Markus, Decher, Niels, Kockskämper, Jens
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	CACNA1C cardiomyocyte Biowissenschaften, Biologie calcium handling remodeling Life sciences
Online Access:	PDF Full Text
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