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Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats

CACNA1C encodes the pore-forming α1C subunit of the L-type Ca2+ channel, Cav1.2. Mutations and polymorphisms of the gene are associated with neuropsychiatric and cardiac disease. Haploinsufficient Cacna1c+/− rats represent a recently developed model with a behavioral phenotype, but its cardiac pheno...

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Main Authors: Fender, Hauke, Walter, Kim, Kiper, Aytug K., Plačkić, Jelena, Kisko, Theresa M., Braun, Moria D., Scharting, Rainer K. W., Rohrbach, Susanne, Wöhr, Markus, Decher, Niels, Kockskämper, Jens
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
Subjects:
CACNA1C
cardiomyocyte
Biowissenschaften, Biologie
calcium handling
remodeling
Life sciences
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Call Number: urn:nbn:de:hebis:04-es2024-04507
Publication Date: 2024-01-18
Source: Erstveröffentlichung: Fender, H.; Walter, K.; Kiper, A.K.; Plačkić, J.; Kisko, T.M.; Braun, M.D.; Schwarting, R.K.W.; Rohrbach, S.; Wöhr, M.; Decher, N.; et al. Calcium Handling Remodeling Underlies Impaired Sympathetic Stress Response in Ventricular Myocardium from Cacna1c Haploinsufficient Rats. Int. J. Mol. Sci. 2023, 24, 9795. https://doi.org/10.3390/ijms24129795
Downloads: 42 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0450
https://doi.org/10.3390/ijms24129795

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