Dying transplanted neural stem cells mediate survival bystander effects in the injured brain

Neural stem and progenitor cell (NSPC) transplants provide neuroprotection in models of acute brain injury, but the underlying mechanisms are not fully understood. Here, we provide evidence that caspase-dependent apoptotic cell death of NSPCs is required for sending survival signals to the injured b...

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Main Authors: Han, Wei, Meißner, Eva-Maria, Neunteibl, Stefanie, Günther, Madeline, Kahnt, Jörg, Dolga, Amalia, Xie, Cuicui, Plesnila, Nikolaus, Zhu, Chaglian, Blomgren, Klas, Culmsee, Carsten
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
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Call Number: urn:nbn:de:hebis:04-es2024-04335
Publication Date: 2024-01-17
Source: Erstveröffentlichung: Han, W., Meißner, EM., Neunteibl, S. et al. Dying transplanted neural stem cells mediate survival bystander effects in the injured brain. Cell Death Dis 14, 173 (2023). https://doi.org/10.1038/s41419-023-05698-z
Downloads: 59 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0433
https://doi.org/10.1038/s41419-023-05698-z