Bacterial vesicles block viral replication in macrophages via TLR4‑TRIF‑axis

Gram-negative bacteria naturally secrete nano-sized outer membrane vesicles (OMVs), which are important mediators of communication and pathogenesis. OMV uptake by host cells activates TLR signalling via transported PAMPs. As important resident immune cells, alveolar macrophages are located at the ai...

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Main Authors: Bierwagen, Jeff, Wiegand, Marie, Laakmann, Katrin, Danov, Olga, Limburg, Hannah, Herbel, Stefanie Muriel, Heimerl, Thomas, Dorna, Jens, Jonigk, Danny, Preußer, Christian, Bertrams, Wilhelm, Braun, Armin, Sewald, Katherina, Schulte, Leon N., Bauer, Stefan, Pogge von Strandmann, Elke, Böttcher-Friebertshäuser, Eva, Schmeck, Bernd, Jung, Anna Lena
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
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Call Number: urn:nbn:de:hebis:04-es2024-04293
Publication Date: 2024-01-17
Source: Erstveröffentlichung: Bierwagen, J., Wiegand, M., Laakmann, K. et al. Bacterial vesicles block viral replication in macrophages via TLR4-TRIF-axis. Cell Commun Signal 21, 65 (2023). https://doi.org/10.1186/s12964-023-01086-4
Downloads: 32 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0429
https://doi.org/10.1186/s12964-023-01086-4