Generation of a Syngeneic Heterozygous ACVRL1(wt/mut) Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis

Hereditary hemorrhagic telangiectasia (HHT) type 2 is an autosomal dominant disease in which one allele of the ACVRL1 gene is mutated. Patients exhibit disturbances in TGF-beta/BMP-dependent angiogenesis and, clinically, often present with severe nosebleeds as well as a reduced quality of life. The...

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Main Authors: Xiang-Tischhauser, Li, Bette, Michael, Rusche, Johanna R., Roth, Katrin, Kasahara, Norio, Stuck, Boris A., Bakowsky, Udo, Wartenberg, Maria, Sauer, Heinrich, Geisthoff, Urban W., Mandic, Robert
Format: Article
Language:English
Published: Philipps-Universität Marburg 2023
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Call Number: urn:nbn:de:hebis:04-es2024-04263
Publication Date: 2024-01-17
Source: Erstveröffentlichung: Xiang-Tischhauser, L.; Bette, M.; Rusche, J.R.; Roth, K.; Kasahara, N.; Stuck, B.A.; Bakowsky, U.; Wartenberg, M.; Sauer, H.; Geisthoff, U.W.; et al. Generation of a Syngeneic Heterozygous ACVRL1(wt/mut) Knockout iPS Cell Line for the In Vitro Study of HHT2-Associated Angiogenesis. Cells 2023, 12, 1600. https://doi.org/10.3390/cells12121600
Downloads: 34 (2024)
License: https://creativecommons.org/licenses/by/4.0
Access URL: https://archiv.ub.uni-marburg.de/es/2024/0426
https://doi.org/10.3390/cells12121600