Functional Characterization of a Spectrum of Novel Romano-Ward Syndrome KCNQ1 Variants

The KCNQ1 gene encodes the α-subunit of the cardiac voltage-gated potassium (Kv) channel KCNQ1, also denoted as Kv7.1 or KvLQT1. The channel assembles with the ß-subunit KCNE1, also known as minK, to generate the slowly activating cardiac delayed rectifier current IKs, a key regulator of the heart r...

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Bibliographic Details

Main Authors:	Rinné, Susanne, Oertli, Annemarie, Nagel, Claudia, Tomsits, Philipp, Jenewein, Tina, Kääb, Stefan, Kauferstein, Silke, Loewe, Axel, Beckmann, Britt Maria, Decher, Niels
Format:	Article
Language:	English
Published:	Philipps-Universität Marburg 2023
Subjects:	potassium channel KCNQ1 KvLQT1 Medizin LQTS Romano-Ward syndrome Medical sciences Medicine
Online Access:	PDF Full Text
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